An Integrative Framework for Bayesian Variable Selection with Informative Priors for Identifying Genes and Pathways
نویسندگان
چکیده
منابع مشابه
An Integrative Framework for Bayesian Variable Selection with Informative Priors for Identifying Genes and Pathways
The discovery of genetic or genomic markers plays a central role in the development of personalized medicine. A notable challenge exists when dealing with the high dimensionality of the data sets, as thousands of genes or millions of genetic variants are collected on a relatively small number of subjects. Traditional gene-wise selection methods using univariate analyses face difficulty to incor...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2013
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0067672